All models
ClearanceProduction
Intrinsic Clearance
Regresses intrinsic clearance from microsomal or hepatocyte context, feeding directly into physiologically based clearance and PK projections.
Input
SMILES + assay system
Output
CLint (µL/min/mg protein) with uncertainty band
API
Available now
Architecture
Ensemble of graph neural networks
Example metrics
RMSE (demo)0.38 log units
MAE (demo)0.29 log units